Application
PD123,319 di (trifluoroacetate) salt hydrate has been used in following experimental studies:
- To determine the effect of Angiotensin II (Ang II) on alveolar fluid clearance (AFC).
- To study the effect of PD123319 on AngII-induced abdominal aortic aneurysms (AAAs).
- To study its effect on Ang II-induced LRP1 overexpression and function in vascular smooth muscle cells (VSMCs) culture.
Biochem/physiol Actions
PD123,319 di (trifluoroacetate) salt hydrate is a widely used angiotensin II subtype-2 receptor (AT2R) antagonist to study the role of AT2 receptor in vitro and in vivo. It increases the AngII-induced abdominal aortic aneurysms (AAAs) without interacting with AT2 receptor.
Caution
Hygroscopic
Legal Information
Sold with permission of Warner-Lambert Company.
- UPC:
- 51433928
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- P186-10MG
- CAS:
- 136676-91-0