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pdc31 (c09-1165-132)

PDC31 (C09-1165-132)

Aladdin

Catalog No.
C09-1165-132
Manufacturer No.
P651839-1mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $83.29
List Price: $92.55

PDC31 (THG113.31: ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor . PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine

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PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor . PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contractions in vivo, which can be used for research of preterm labor and primary dysmenorrhea (PD). PDC31 also enhances Ca 2+ -dependent large-conductance K + -channel in human myometrial cellsIn VitroPDC31 (10 μM, 50 μM; ) stimulates the BK Ca channel in human myometrial smooth muscle cells, and enhances open state channel activity with average 4 and 6-fold by 10 and 50 μM, respectively. PDC31 (1 nM-10 μM; 20 min intervals) cumulatively inhibits spontaneous contractions in isolated pregnant human myometrium. PDC31 consists of ILGHXDYK, associated sequence is based on a transmembrane domain of the human PGF2a receptor. PDC31 has been shown to reduce the duration and strength of PGF2a-induced contractions in myometrial strip models and to delay delivery in animal models of preterm labor . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:FP Receptor ~30 nM (Ki) PGF 2α. Specification: 0.99 Molecular Formula: C45H71N13O13 Molecular Weight: 1002.12
UPC:
12352005
Condition:
New
Availability:
8-12 weeks
Weight:
1.06 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
P651839-1mg
CAS:
634586-40-6
Product Size:
1mg


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