PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC 50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B , respectively.Appearance:SolidIC50& Target:NMDA ReceptorIn Vitro:PEAQX (3 μM) produces similar caspase-3 activation, while NVP-AAM007 is approximately three-fold more potent. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In Vivo:PEAQX (10-40mg/kg) dose-dependently increased cortical caspase-3 activity following sub-chronic administration. ?/nPEAQX (10 and 20mg/kg) shows enhanced locomotor activity in response to PCP challenge (4mg/kg on PN28-35) compared to saline pretreaBiological Activity:PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC 50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B , respectively. Specification: ≥98% Molecular Formula: C17H15BrN3Na4O6P Molecular Weight: 560.15
- UPC:
- 51182057
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- P659250-5mg
- Product Size:
- 5mg
