Biochem/physiol Actions PFI-7 is a high affinity E3 ligase GID4 probe (KD = 0.08 μ:M by SPR) that competes against cellular degrons for full-length GID4 binding with high potency (EC50 = 0.
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PFI-7 is a high affinity E3 ligase GID4 probe (KD = 0.08 μM by SPR) that competes against cellular degrons for full-length GID4 binding with high potency (EC50 = 0.6 μM by cell-based NanoBRET).
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