PIMECROLIMUS (C005B-312110)

Catalog No.: C005B-312110
Mfr. No.: SML1437-10MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: MG

Price: $314.47

List Price: $349.41

Biochem/physiol Actions Pimecrolimus is known for its anti-inflammatory and immunomodulatory properties and its low systemic immunosuppressive potential. Pimecrolimus, also known as Picrolimus, is a macrolactam ascomycin derivative that acts as

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Biochem/physiol Actions

Pimecrolimus is known for its anti-inflammatory and immunomodulatory properties and its low systemic immunosuppressive potential.

Pimecrolimus, also known as Picrolimus, is a macrolactam ascomycin derivative that acts as an immune suppressant. It binds with high affinity to macrophilin-12 (FKBP-12) and inhibits calcineurin, a calcium-dependent phosphatase. Pimecrolimus inhibits production of pro-inflammatory cytokines by T cells and mast cells and prevents the release of inflammatory cytokines and mediators from mast cells. It has been used clinically as a treatment for eczema.

UPC:: 51111652
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML1437-10MG
CAS:: 137071-32-0

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