General description
Piperidine, a heterocyclic cyclohexane is a volatile secondary amine. Maxam-Gilbert chemical method, a DNA sequencing technology employs piperidine to rupture DNA strands at damaged base site. Its crystal structure analyzed at 150K shows hydrogen bonding between NH groups. Piperidine ring forms a part of many naturally occuring alkaloids. It is prepared on an industrial scale by the hydrogenation of pyridine in the presence of nickel catalyst. The 1H NMR spectrum of piperidine has been recorded.
Application
Fits Applied Biosystems 431 and 433A peptide synthesizers.
Piperidine has been used in combination with DMF (dimethylformamide) for the removal of Fmoc (fluorenylmethyloxycarbonyl) group from the N-terminal amino group during peptide synthesis.
- UPC:
- 51294500
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 571261-450ML
