General description
PK150 is a recently discovered small antimicrobial compound. It is a potent analog of sorafenib, an anticancer drug. PK150 has structural similarity with triclocarban (TCC) and triclosan (TCS) with a N,N′-diaryl urea motif in common.
Biochem/physiol Actions
PK150 is a potent antibiotic, which displays strong antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) at a sub-micromolar level. It elicits anti-biofilm activity and eliminates persisters. PK150 also shows oral bioavailability, and in vivo efficacy in mouse model.
- UPC:
- 51112000
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SBR00043-10MG
- CAS:
- 2165324-62-7