General description
A potent and competitive inhibitor of PKA (Ki = 1.7 nM).
A potent and competitive inhibitor of protein kinase A (Ki = 1.7 nM).
Biochem/physiol Actions
Cell permeable: no
Primary Target
PKA
Product does not compete with ATP.
Reversible: no
Target Ki: 1.7 nM against protein kinase A
Packaging
Yes
Warning
Toxicity: Standard Handling (A)
Sequence
H-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH₂
Physical form
Supplied as a trifluoroacetate salt.
Reconstitution
Following initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Glass, D.B., et al. 1989. J. Biol. Chem. 264, 8802.
Kemp, B.E., et al. 1988. Methods Enzymol.159, 173.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51286505
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 539684-1MG