PKC ζ Pseudo-substrate inhibitor, Myristoylated

PKC ζ Pseudo-substrate inhibitor, Myristoylated (ZIP) is a cell-permeable, reversible, substrate competitive, myristoylated form of the protein kinase C ζ isozyme pseudosubstrate inhibitory peptide (sc-3098) found to inhibit an atypical type of Protein Kinase C ζ (zeta). PKC ζ Pseudo-substrate inhibitor, Myristoylated has been shown to also interact with PKC family isoforms and disrupt conventional PKC targeting and translocation leading to physiological memory impairment. The sequence corresponds to the pseudosubstrate region of the N-terminal regulatory domain that maintains the enzyme in an inactive form in the absence of activator. PKC ζ Pseudo-substrate inhibitor, Myristoylated has also been shown to be a competitive inhibitor of PKC ζ in neurons. PKC ζ Pseudo-substrate inhibitor, Myristoylated was also used to demonstrate that PKC ζ is involved in the regulation of integrin-dependent adhesion and chemotaxis of intact human neutrophils.PKC ζ Pseudo-substrate inhibitor, Myristoylatedis a cell-permeable form of the PKC ζ isozyme pseudosubstrate inhibitory peptide. Specifications and Purity: ≥95%. Molecular Formula: C90H154N30O17. Molecular Weight: 1928.5. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/P378896-SCI_a6efcffcf32cf9c33b84f4b1f89ef2d3.pdf.