Name: Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)-block-decane (C15-1308-751)
SKU: C15-1308-751
Price: 1140 USD
Availability: InStock

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)-block-decane (C15-1308-751)

Catalog No.

C15-1308-751

Manufacturer No.

764736-1G

Manufacturer Name

Sigma-Aldrich

Quantity

Unit of Measure

Price: $1,140.00

List Price: $1,266.67

Block copolymer micelles are widely used in drug delivery applications. PEG-PDLLA is a biodegradable polymeric micelle which is used as a carrier for hydrophobic drugs like Paclitaxel.

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Description
Specifications

General description

Block copolymer micelles are widely used in drug delivery applications. PEG-PDLLA is a biodegradable polymeric micelle which is used as a carrier for hydrophobic drugs like Paclitaxel. The hydrophilic PEG and hydrophobic PDLLA form the micelle core wherein the hydrophobic drug is loaded. The incorporation of the 10-alkyl end cap (decane) increases the hydrophobicity of the micelle core and increases its solubilizing capability for hydrophobic drugs.â€

Application

Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs.

Features and Benefits

Good biocompatibility, low immunogenicity and good degradability.
Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

form: pellets. Quality Level: 100. mol wt: PDLLA average M_n 2,000, PEG average M_n 2,000, average M_n 4,000 (total). degradation timeframe: 2-5 . weeks. transition temp: T_m 29-33 . Â°C. PDI: <. 1.1 (typical PEG), <. 1.2, <. 1.3 (overall). storage temp.: 2-8Â°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): 230.0 Â°F. Flash Point(C): > 110 Â°C.