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Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide) (C15-1308-755)

Catalog No.
C15-1308-755
Manufacturer No.
764817-1G
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
GR
Price: $1,040.57
List Price: $1,156.19

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the

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General description

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Features and Benefits

Biocompatible, degradable, thermosensitive, high stability, small size (<200 nm) and properties can be easily modified.

description: typical PEG PDI<. 1.1. overall PDI≤. 2.0 (THF, PS). Quality Level: 100. form: semisolid. feed ratio: lactide:glycolide 75:25. mol wt: PEG average Mn 1,000, PLGA average Mn 2,200, average Mn (1100-1000-1100). degradation timeframe: 2-3 . weeks. transition temp: Tm 230-235 . °C. PDI: <. 2.0. storage temp.: 2-8°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
UPC:
51202003
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
764817-1G


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