POLY(OLIGOETHYLENE GLYCOL METHACRYLATE (C15-1313-607)

General description

Poly(oligo(ethylene glycol) methacrylate) (POEGMA) is a family of polymers consisting of a hydrophobic methacrylate backbone and hydrophilic ethylene oxide (EO) side groups with highly branched architecture. The highly branched architecture with a high density of oligo EO moities enhances the solubility of the polymer in water.

Application

• Drug delivery- enhances the stability and delivery of siRNA and eliminates PEG antigenicity
• Biosensor coatings- provides an anti-fouling surface
• Stimuli-responsive hydrogels for tissue engineering, drug delivery, and other biomedical applications

Poly(oligo(ethylene glycol) methyl ether methacrylate) (POEGMA) is a family of polymers consisting of a hydrophobic methacrylate backbone and hydrophilic ethylene oxide (EO) side groups with highly branched architecture . The side chain EO segments enhance the solubility of the polymer in water , exhibiting many interesting properties such as non-fouling , stealth, anti-PEG antibodies & thermo-responsive behaviors.

Features and Benefits

• Highly branched architecture and high density of oligo ethylene oxide moieties
• Water soluble
• Nonfouling and thermo-responsive behaviors
• Viable alternative to PEG in biological and biomaterial applications

linearFormula: C₆H₈NO₂[C₄H₅O₂(C₂H₄O)_x]_nOH. form: liquid. Quality Level: 100. mol wt: 80,000-130,000. color: colorless. storage temp.: −. 20°C. Storage Class Code: 10 - Combustible liquids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.