Polyunsaturated Fatty Acid LC-MS Mixture

Features Each vial contains a mixture of standards packaged in amber ampules purged with argon >1 ml provided at the concentration specified in the insert Designed for direct snap and inject use in mass spectrometry applications Ideally suited for method development and as a system suitability standard This mixture contains various polyunsaturated fatty acids, including many important essential fatty acids. The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS applications. The solution may be serially diluted for preparation of calibrators and QC standards and/or used directly as a system suitability standard or tuning standard. After opening, we recommend that the mixture be transferred immediately to a 1 ml glass screw cap vial, to prevent solvent evaporation, and stored at -20°C. The mixture should be discarded after multiple freeze/thaw cycles. The polyunsaturated fatty acids represented in this mixture are composed of 18-22 carbons and include many of the key ω-3 and ω-6 fatty acids. These compounds are either produced endogenously or found naturally in plants and marine organisms and most have significant biological roles as eicosanoid precursors. Some compounds have also demonstrated protective effects against inflammatory diseases, coronary heart disease, thrombosis, or ischemic brain injury.