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pomalidomide-peg2-c2-azide

POMALIDOMIDE-PEG2-C2-AZIDE

Catalog No.
C15-1224-365
Mfr. No.
930563-50MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
50
UOM
MG
Price: $542.86
List Price: $603.18

Application Pomalidomide-PEG 2 -C 2 -azide is a functionalized cereblon ligand for development of pomalidomide-based PROTACs. Contains an alkyne, allowing for conjugation through click chemistry.

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Application

Pomalidomide-PEG2-C2-azide is a functionalized cereblon ligand for development of pomalidomide-based PROTACs. Contains an alkyne, allowing for conjugation through click chemistry. A basic building block for development of a protein degrader library.


Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation


Protein Degrader Building Blocks

Other Notes

Targeted Protein Degradation by Small Molecules

Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG

Small-Molecule PROTACS: New Approaches to Protein Degradation

Targeted Protein Degradation: from Chemical Biology to Drug Discovery

Impact of linker length on the activity of PROTACs

Shipping Information:

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UPC:
51201824
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
930563-50MG
CAS:
2271036-45-2
Temperature Control Device:
Yes

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