POSACONAZOLE (C15-1722-709)

Sigma Aldrich

Catalog No.: C15-1722-709
Manufacturer No.: SML2287-25MG
Manufacturer Name: Sigma-Aldrich
Quantity: 25
Unit of Measure: MG

Price: $987.94

List Price: $1,097.71

Application Posaconazole has been used: in antifungal susceptibility testing of Aspergillus terreus as a lanosterol :14α:-demethylase (CYP51)-specific inhibitor to study its effects on membrane permeability in Candida albicans

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Description
Specifications

Application

Posaconazole has been used:

in antifungal susceptibility testing of Aspergillus terreus
as a lanosterol 14α-demethylase (CYP51)-specific inhibitor to study its effects on membrane permeability in Candida albicans cells
to study its effects on promastigotes

Biochem/physiol Actions

Posaconazole is a highly potent broadspectrum antifungal agent against the yeast infection caused especially by Candida sp. It blocks the growth of fungi by inhibiting the enzyme lanosterol 14α-demethylase (CYP51). In contrast to other antifungal azoles, posaconazole has been reported not to induce the efflux pump mechanism. Posaconazole exhibits antichagasic effects against different strains of Trypanosoma cruzi causing Chagas disease.

UPC:: 51303404
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: SML2287-25MG
Product Size:: 25/MG
CAS:: 171228-49-2

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