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Prostaglandin F2a methyl ester-1 mg

Catalog No.
C08-0322-921
Manufacturer No.
16011-1
Manufacturer Name
Cayman Chemical Company
Quantity
1
Unit of Measure
EA
Price: $147.01
List Price: $163.34
*Additional Hazmat Fee will apply

PGF2&alpha methyl ester is an analog of PGF2&alpha in which the C-1 carboxyl group has been esterified as the methyl ester. PGF2&alpha methyl ester was one of the first PG esters shown to have ocular hypotensive activity.

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PGF2α methyl ester is an analog of PGF2α in which the C-1 carboxyl group has been esterified as the methyl ester. PGF2α methyl ester was one of the first PG esters shown to have ocular hypotensive activity. This compound continues to be a standard by which other ocular hypotensive PG prodrugs are evaluated. The methyl ester is about 4-5 times more potent than the free acid, PGF2α. This difference is attributed to improved corneal penetration, and a depot effect of prolonged retention of the ester form of the compound in ocular tissue. A 2.5 µg dose of PGF2α-OMe applied to the eyes of cats results in a 6-8 mm Hg reduction in IOP.
UPC:
12350000
Condition:
New
Availability:
3 Days
Weight:
1.00 Ounces
HazMatClass:
Yes
WeightUOM:
LB
MPN:
16011-1


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