Prostaglandin F2a methyl ester-500 ÃƒÆ’Ã†â¦g

Catalog No.: C003B-360890
Mfr. No.: 16011-500
Mfr. Name: Cayman Chemical Company
Qty/UOM: 1
UOM: EA

Price: $105.41

List Price: $117.12

PGF2&alpha methyl ester is an analog of PGF2&alpha in which the C-1 carboxyl group has been esterified as the methyl ester. PGF2&alpha methyl ester was one of the first PG esters shown to have ocular hypotensive activity.

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Description
Specifications

PGF2α methyl ester is an analog of PGF2α in which the C-1 carboxyl group has been esterified as the methyl ester. PGF2α methyl ester was one of the first PG esters shown to have ocular hypotensive activity. This compound continues to be a standard by which other ocular hypotensive PG prodrugs are evaluated. The methyl ester is about 4-5 times more potent than the free acid, PGF2α. This difference is attributed to improved corneal penetration, and a depot effect of prolonged retention of the ester form of the compound in ocular tissue. A 2.5 µg dose of PGF2α-OMe applied to the eyes of cats results in a 6-8 mm Hg reduction in IOP.

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UPC:: 51385809
Condition:: New
Availability:: 3 Days
Weight:: 1.00 Ounces
HazmatClass:: Yes
WeightUOM:: LB
MPN:: 16011-500

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