General description
A fluorogenic substrate for assaying trypsin-like activity of proteasome. Also serves as a substrate for cathepsin B. Excitation max: 360-380 nm; emission max.: 430-460 nm.
A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome. Also reported to be a specific substrate for cathepsin B.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Proteasome
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Warning
Toxicity: Standard Handling (A)
Sequence
Z-Ala-Arg-Arg-AMC
Physical form
Supplied as hydrochloride salt.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C
Other Notes
Geier, E., et al. 1999. Science283, 978.
Dick, T.P., et al. 1998. J. Biol. Chem. 273, 25637.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 41141946
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 539149-5MG
- CAS:
- 90468-18-1
