Complement Proteins

Protein Purity≥85% by SDS PAGEExtinction CoeffA280 nm = 1.016 at 1.0 mg/ml for pure C3Molecular Weight175,000 Da (2 chains)General DescriptionRat C3b is derived from native purified rat C3 upon cleavage and release of C3a with the alternative

Purity&gt90% by SDS-PAGEExtinction Coeff. A280 nm = 1.10 at 1.0 mg/mLMolecular Weight 139,000 Da (3 chains)PrecautionsUse normal precautions for handling human blood productsGeneral DescriptionC3c is derived from iC3b (inactivated C3b) by

Protein Purity&gt95% by SDS-PAGEExtinction Coeff.A280 nm = 1.10 at 1.0 mg/mlMolecular Weight33,800 Da (single chain)General DescriptionC3d is derived from human C3 after a series of proteolytic cleavages. Trypsinlike enzymes (such as plasmin,

Protein Purity&gt90% by SDS-PAGEExtinction Coeff.A280 nm = 1.03 at 1.0 mg/mLMolecular Weight205,000 Da (3 chains)General DescriptionNative human C4 is a naturally glycosylated polypeptide containing three disulfide-linked chains. C4 is central to

Protein Purity&gt90% by SDS-PAGEExtinction Coeff.A280 nm = 1.03 at 1.0 mg/mLMolecular Weight205,000 Da (3 chains)General DescriptionNative human C4 is a naturally glycosylated (6.9%) polypeptide containing three disulfide-linked chains. C4 is

PurityNo C4 detectable by hemolytic assayPrecautionsUse normal precautions for handling animal blood productsGeneral DescriptionC4-deficient guinea pigs were characterized in 1971 as being completely genetically and functionally deficient in C4

Protein Purity&gt95% by SDS-PAGEExtinction Coeff.A276 nm = 0.456 at 1.0 mg/mLMolecular Weight8,759 Da (single chain)General DescriptionNatural human C4a is prepared by cleavage of human C4 protein by human C1s. It is produced during activation of

Protein Purity&gt95% by SDS-PAGEExtinction Coeff.A276 nm = 0.456 at 1.0 mg/mLMolecular Weight8,603 Da (single chain)General DescriptionNatural human C4a is prepared by cleavage of human C4 protein by human C1s. It is produced during activation of

Protein Purity&gt90% by SDS-PAGEExtinction Coeff.A280 nm = 1.03 at 1.0 mg/mLGeneral DescriptionC4b is derived from native C4 upon proteolytic cleavage by C1s and release of C4a. C4b is central to the function of both the classical and lectin

Protein Purity&gt90% by SDS-PAGEExtinction Coeff.A280 nm = 1.03 at 1.0 mg/mLMolecular Weight540,000 Da (8 chains)General DescriptionC4b binding protein (C4BP) regulates complement activation of the classical and lectin pathways. It binds to C4b and

Protein Purity&gt95% by SDS-PAGEExtinction Coeff.A280 nm = 1.03 at 1.0 mg/mLMolecular Weight190,000 Da (2 chains)General DescriptionNative human C5 is a naturally glycosylated (1.6%) polypeptide containing two disulfide-linked chains. C5 is

Protein Purity&gt97% by SDS-PAGEExtinction Coeff.A280 nm = 0.41 at 1.0 mg/mlMolecular Weight10,400 Da (single chain)General DescriptionNatural human C5a is prepared from human C5 protein by cleavage of the peptide bond between C5a and C5b by the