PRT4165 (C005B-312662)

Catalog No.: C005B-312662
Mfr. No.: SML1013-25MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 25
UOM: MG

Price: $802.70

List Price: $891.89

Biochem/physiol Actions PRT4165 is a potent inhibitor of PRC1 (polycomb-repressive complex 1)-mediated histone H2A ubiquitylation in vivo and in vitro . PRT4165 inhibits the in vitro histone H2A E3 ubiquitin ligase activity of PRC1

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Biochem/physiol Actions

PRT4165 is a potent inhibitor of PRC1 (polycomb-repressive complex 1)-mediated histone H2A ubiquitylation in vivo and in vitro. PRT4165 inhibits the in vitro histone H2A E3 ubiquitin ligase activity of PRC1 components RING1, RNF2, and a BMI1/RNF2 complex. PRT4165 also inhibits DNA double-strand breaks induced ubiquitylation of histone H2AX.

Features and Benefits

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UPC:: 51112405
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML1013-25MG
CAS:: 31083-55-3

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