PYR10 (C005B-312367)

Catalog No.: C005B-312367
Mfr. No.: SML1243-25MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 25
UOM: MG

Price: $692.31

List Price: $769.23

Biochem/physiol Actions Pyr10 is a novel, selective inhibitor of the transient receptor potential channel TRPC3. Pyr10 blocks carbachol-induced calcium entry into TRPC3-transfected HEK293 cells (IC 50 = 0.

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Description
Specifications

Biochem/physiol Actions

Pyr10 is a novel, selective inhibitor of the transient receptor potential channel TRPC3. Pyr10 blocks carbachol-induced calcium entry into TRPC3-transfected HEK293 cells (IC₅₀ = 0.72 μM), with significantly lower activity against STIM1/Orai1 mediated release of calcium from endoplasmic reticulum (store operated calcium entry) in BRL-2H3 cells (IC₅₀ = 13.08 μM).

UPC:: 51172815
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML1243-25MG
CAS:: 1315323-00-2

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