Pyronin Y (C09-0998-871)

Pyronin Y is a dye that intercalates and stains RNA red, and has been shown to accumulate in the mitochondria of viable cells. Multidrug-resistant (MDR) Acinetobacter baumannii studies tested inhibition of the efflux pump by measuring the intracellluar accumulation of Pyronin Y and Ethidium bromide. Research shows that at low Pyronin Y concentrations the cytostatic effect is cell arrest in the G1 phase, whereas at high concentrations the cells arrest is in the G2 and S phase. Pyronin Y has been used in combination with Alcian Blue to asses and study pulmonary diseases, and in combination with Methyl Green to stain nucleic acids in paraffin sections. Additionally Pyronin Y has been used to measure RNA in flow cytometry.Used in Unna-Pappenheim stain to demonstrate RNA (red) in contrast to DNA (green). Also used for bacteria staining. Specification: biological stain MDL Number: MFCD00011725 Molecular Formula: C17H19ClN2O Molecular Weight: 302.81 PubChem CID: 7085 Isomeric SMILES: CN(C)C1=CC2=C(C=C1)C=C3C=CC(=[N+](C)C)C=C3O2.[Cl-] Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/P100851-SCI_56fd303364bbdd898a83c308d71e061a.pdf