Application
Pyrylium tetrafluoroborate is used for the functionalization of heterocyclic amines, activating them for nucleophilic substitution. As demonstrated by the Cornella lab, the intermediate pyridinium salts can react with a vast array of nucelophiles to form new C-N, C-O, and C-S bonds, making pyrylium tetrafluoroborate a valuable reagent for late-stage functionalization.
Other Notes
Selective Functionalization of Aminoheterocycles by a Pyrylium Salt
Selective Late-Stage Sulfonyl Chloride Formation from Sulfonamides Enabled by PyryBF4
Synthesis of Sulfonyl Fluorides from Sulfonamides
- UPC:
- 51332881
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 906719-5G