Q-dextran (C09-1022-420)

Q-dextran is a polycationic derivative of dextran. These derivatives are distinct from DEAE-dextrans in that they only contain quaternary amine groups. Unlike DEAE-dextrans, Q-dextrans will be charged over a wide range of pH (pH 4-10). Q-dextrans will also have a much stronger net charge than corresponding DEAE-dextrans. All batches are checked for molecular weight, degree of substitution and loss on drying. Aladdin produce Q-dextran from 4 kDa to 150 kDa. Q-dextrans are supplied as a white powder.StructureQ-dextrans are synthesised by reacting dextran fractions with 2,3-epoxypropyltrimethylammonium chloride. The nitrogen content is approximately 2% which corresponds to one quaternary ammonium group for every four glucose units.ApplicationPolycationic products exhibit a wide variety of effects in cellular systems and are of interest as adjuvants in vaccines. Q-dextran has a much stronger net charge than corresponding DEAE-dextrans and will thus give enhanced responses in systems where this effect is important. Specification: 10 kDa Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/Q292454-SCI_93282c969b90502fd0364d6b29886c70.pdf