R 268712 (C09-1509-800)

Aladdin

Catalog No.: C09-1509-800
Manufacturer No.: R286557-100mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: Each

Price: $385.58

List Price: $428.42

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Description
Specifications

R-268712 is an orally active and selective ALK-5 inhibitor, with an IC50 of 2.5 nM. R-268712 inhibits the phosphorylation of Smad3 in a dose-dependent manner with an IC50 of 10.4 nM. R-268712 suppresses glomerulonephritis as well as glomerulosclerosis by inhibiting TGF-β signaling, which can be used in studies of renal fibrosis and cancer. Specifications and Purity: ≥98%(HPLC) Molecular Formula: C₂₀H₁₈FN₅O Molecular Weight: 363.39 PubChem CID: 11703284 Isomeric SMILES: CC1=NC(=CC=C1)C2=C(C=NN2)C3=CC(=C(C=C3)F)C4=CN(N=C4)CCO Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/R286557-SCI_cde214dfb63fecb4cb84e7e8848293ef.pdf

UPC:: 41106305
Condition:: New
Availability:: 8-12 weeks
Weight:: 1.06 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: R286557-100mg
CAS:: 879487-87-3
Product Size:: 100mg
Hazard Statement Codes:: H335:H319:H315:H302
Precautionary Statement Codes:: P305+P351+P338:P261

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