R(+)-Baclofen hydrochloride (C15-1254-995)

Catalog No.: C15-1254-995
Manufacturer No.: G013-100MG
Manufacturer Name: Sigma-Aldrich
Quantity: 100
Unit of Measure: MG

Price: $1,177.71

List Price: $1,308.57

Application R(+)-Baclofen hydrochloride has been used as a GABA B receptor agonist to study its effects on M43068-induced antinociception in rat models. It has also been used as a GABA B receptor agonist to study its effects on amphetamine-induced

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Description
Specifications

Application

R(+)-Baclofen hydrochloride has been used as a GABA_B receptor agonist to study its effects on M43068-induced antinociception in rat models. It has also been used as a GABA_B receptor agonist to study its effects on amphetamine-induced behavior and neurochemical responses in rat striatum.

Biochem/physiol Actions

Baclofen is a derivative of γ-aminobutyric acid (GABA) and acts as a 4-aminobutanoic acid receptor (GABA_B) agonist. It interacts stereospecifically with the GABA receptor and exhibits antispastic effects.Baclofen shows therapeutic effects against paroxysmal pain of trigeminal neuralgia and spinal spasticity. R(+)-Baclofen is a more active enantiomer.

Other Notes

Same enantiomer as R(−)-baclofen free base.

UPC:: 51152050
Condition:: New
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: G013-100MG

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