(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC 50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragmentIn Vitro(R)-PS210 displays an AC 50 value of 1.8 μM towards PDK1 in a Cell-Free Kinase Activity Assay. And the maximum activation of PDK1 compared to DMSO control of (R)-PS210 is 5.5 fold. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:AC50: 1.8 μM (PDK1). Specification: 0.98 Molecular Formula: C19H15F3O5 Molecular Weight: 380.31
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- P650497-50mg
- CAS:
- 1410101-89-1
- Product Size:
- 50mg
