RA375 is a RPN13 (26S proteasome regulatory subunit) inhibitor. RA375 activates UPR signaling, ROS production and apoptosis . RA375 exhibits ten-fold greater activity against cancer lines than RA190, reflecting its nitro ring substituents and the additionAppearance:SolidIn Vivo:RA375 (10mg/kg, ip) inhibits proteasome function and reduces ovarian tumor burden in mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: RA375 (10mg/kg, ip) inhibits proteasome functioBiological Activity:RA375 is a RPN13 (26S proteasome regulatory subunit) inhibitor. RA375 activates UPR signaling, ROS production and apoptosis . RA375 exhibits ten-fold greater activity against cancer lines than RA190, reflecting its nitro ring substituents and the addition. Specification: 0.99 Molecular Formula: C30H25ClN4O7 Molecular Weight: 589
- UPC:
- 12352200
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- R658797-100mg
- Product Size:
- 100mg
