Immunogen
The epitope recognized by PLA0043 maps to a region between residues 425 and the C-terminus (residue 482) of human REST (RE1-silencing transcription factor) corepressor using the numbering given in entry NP_055971.1 (GeneID 23186)
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide
Other Notes
CoREST has been identified as a component of a histone deacetylase (HDAC) complex as well as an interacting protein and corepressor of the REST (repressor element 1 silencing transcription factor) transcription factor. HDAC complexes deacetylate chromatin to repress transcription and silence genes. The CoREST complex may be important in restricting gene expression in a tissue-specific manner.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- UPC:
- 41181706
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- PLA0043-100UL
- Product Size:
- 100/µL
