(Rac)-WAY-161503 is a potent, selective, highly affinity 5-HT 2C receptor agonist with a K i of 4 nM and an EC 50 of 12 nM. (Rac)-WAY-161503 displays higher affinity for 5-HT 2C than 5-HT 2A and 5-HT 2B receptors. (Rac)-WAY-161503 has anti-obesity and antidepressant effects.In Vivo(Rac)-WAY-161503 (3-30 mg/kg; intraperitoneal injection; male C57BL/6J mice) dose-dependently decreases locomotor activity, an effect that is blocked by the 5-HT 2C/2B antagonist SER-082 . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male C57BL/6J mice with hallucinogen 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) Dosage: 3 mg/kg, 10 mg/kg, 30 mg/kg Administration: Intraperitoneal injection (i.p.) Result: Dose-dependently decreased locomotor activity, an effect that was blocked by the 5-HT 2C/2B antagonist SER-082.Form:Solid. Specification: ≥99.0% Molecular Formula: C11H11Cl2N3O Molecular Weight: 272.13 PubChem CID: 21976692 Isomeric SMILES: C1CN2C(CN1)C(=O)NC3=CC(=C(C=C32)Cl)Cl.Cl
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- W649483-5mg
- CAS:
- 75704-24-4
- Product Size:
- 5mg
