RAD51 INHIBITOR B02 (C15-1725-300)

Sigma Aldrich

Catalog No.: C15-1725-300
Manufacturer No.: SML0364-25MG
Manufacturer Name: Sigma-Aldrich
Quantity: 25
Unit of Measure: MG

Price: $1,214.35

List Price: $1,349.27

Application RAD51 Inhibitor B02 has been used: to test its effect on the polar body extrusion (PBE) rate in porcine oocytes for RAD51 inhibition in porcine embryos as RAD51 inhibitor and to test its effect on targeted nucleotide

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Description
Specifications

Application

RAD51 Inhibitor B02 has been used:

to test its effect on the polar body extrusion (PBE) rate in porcine oocytes
for RAD51 inhibition in porcine embryos
as RAD51 inhibitor and to test its effect on targeted nucleotide substitution (TNS) in induced pluripotent stem cells (iPSCs)

Biochem/physiol Actions

B02 (3-(Phenylmethyl)-2-[(1E)-2-(3-pyridinyl)ethenyl]-4(3H)-quinazolinone), a pyridinylvinyl-quinazolinone compound is cell-permeable. B02 inhibits human RAD51 recombinase and subsequent nucleofilaments formation. It halts homologous recombination (HR) repair events in cancer cells. B02 favors apoptosis in multiple myeloma and is crucial for sensitizing them to doxorubicin.

UPC:: 12352200
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: SML0364-25MG
Product Size:: 25/MG
CAS:: 1290541-46-6

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