Raptor Biphenyl Column, 1.8um, 30 x 2.1mm

Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation. The innovative Biphenyl is Restek's most popular LC stationary phase because it is particularly adept at separating compounds that are hard to resolve or that elute early on C18 and other phenyl chemistries. As a result, the rugged Raptor Biphenyl column is extremely useful for fast separations in bioanalytical testing applications like drug and metabolite analyses, especially those that require a mass spectrometer (MS). Increasing retention of early-eluting compounds can limit ionization suppression, and the heightened selectivity helps eliminate the need for complex mobile phases that are not well-suited for MS detection. Stationary Phase Category: Phenyl (L11) Ligand Type: Biphenyl Particle: 2.7 µm or 5 µm superficially porous silica (SPP or "core-shell") Pore Size: 90 Å Carbon Load: 7% (2.7 µm), 5% (5 µm) End-Cap: yes Surface Area: 150 m 2 /g (2.7 µm) or 100 m 2 /g (5 µm) Recommended Usage: pH Range: 1.5–8.0 Maximum Temperature: 80°C Maximum Pressure: 600 bar/8,700 psi (2.7 µm) or 400 bar/5,800 psi (5 µm) Properties: Increased retention for dipolar, unsaturated, or conjugated solutes Enhanced selectivity when used with methanolic mobile phase Ideal for increasing sensitivity and selectivity in LC-MS analyses Switch to a Biphenyl when: Limited selectivity is observed on a C18 You need to increase retention of hydrophilic aromatics Free-Turn architecture lets you change cartridges by hand without breaking inlet/outlet fluid connections—no tools needed Patented titanium hybrid ferrules can be installed repeatedly without compromising high-pressure seal Auto-adjusting design provides ZDV (zero dead volume) connection to any 10-32 female port Maximum cartridge pressure: 1,034 bar/15,000 psi* (UHPLC), 600 bar/8,700 psi (2.7 μm); 400 bar/5,800 psi (5 μm) * For maximum lifetime, recommended maximum pressure for UHPLC particles is 830 bar/12,000 psi.