CD105, also known as endoglin, is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages, and lymphoid and myeloid leukemic cells. Both mouse and human CD105 exhibit >70% sequence homology in their cytoplasmic domains with type III transforming growth factor ß (TGFß) receptor. CD105 has been shown to be one of several receptors for the various isoforms of TGFß which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells, and control of the immune response.
- UPC:
- 51201516
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 1860-26
