Rabbit anti Human DYNLL1/PIN Antibody, Recombinant (R06-4B1), could be used for WB, IHC and so on.Application:WB: 1/500-1/1000IHC: 1/50-1/100Protein FunctionActs as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.Binds and inhibits the catalytic activity of neuronal nitric oxide synthase.Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity. Specifications and Purity: Recombinant (R06-4B1); Rabbit anti Human DYNLL1/PIN Antibody; WB, IHC; Unconjugated.
- UPC:
- 12352203
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Ab100668-10μl
- Product Size:
- 10μl
