Recombinant Human IGF-1 Protein (C09-1095-635)

Purity≥ 95% SDS-PAGE.Molecular weight informatM - 2.84 Da (Calculated mass 7711.84 Da)GP ETLCGAELVD ALQFVCGDRG FYFNKPTGYG SSSRRAPQTG IVDECCFRSC DLRRLEMYCA PLKPAKSAAdditional sequence informationN-terminal glycineFull-length mature chain lacking the signal peptide and both pro-peptides.FunctionThe insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.Product description:Animal origin-Free; Animal viruses-Free; Pathogenic substances-Free; Exogenous factor pollution, High safety.Insulin-like growth factor-1 (IGF-1), also known as growth factor C (SomatamedinC), belongs to the insulin-like growth factor family and has homology with proinsulin in structure. IGF-1 is a peptide growth factor that promotes mitosis, and stimulates the proliferation and survival of various cells such as muscle, bone, and cartilage in vitro. IGF-1 can bind to IGF-1R, IGF-2R and insulin receptors, wake up a variety of signaling pathways, and participate in cell proliferation, differentiation, survival, growth, apoptosis and regeneration. Recombinant human insulin-like growth factor (IGF-1) consists of 70 amino acids and is a bioactive protein used in cell culture.This lyophilized powder is made of recombinant yeast expression, multi-step separation and purification, and then 0.22μm membrane filter sterilization and freeze-drying.Product application：Widely used in cell culture to enhance cell proliferation, cell growth and cell differentiation. Specifications and Purity: Animal Free, >95% SDS-PAGE, Active, E.coli, No tag, 49-188aa.