Product IntroductionInsulin like growth factor-1 (IGF-1) is a hormone with a molecular weight of 7.6kd, and its molecular structure is similar to that of insulin.The main mechanism of action of IGF-1 is to induce signaling within the cell by binding to its specific receptor (IGF1R).IGF-1 is one of the most potent activators of the Akt signaling pathway, which, upon activation, stimulates cell growth and proliferation, and inhibits apoptosis.IGF-1 LR3 adds 13 amino acids to the N-terminus of the intact IGF-1 molecule to form 83 amino acid long-chain IGF-1 and replaces the 3rd amino acid of IGF-1 molecule, glutamic acid (E), with arginine (R), so called R3.IGF-1 LR3 has higher stability and bioactivity than IGF-1 without modification.Specification parametersSource Escherichia coliAppearance white lyophilized powderActivity ≥1.0×106IU/mgpH 6.5-7.5Molecular weight 7.6kDEndotoxin <5EU/mgCAS No 946870-92-4Matters needing attentionReconstitution: it is recommended to reconstitute the rigf-1 LR3 lyophilized powder to 100-200 UG / ml with sterile water and further dilution with other solvents may be performed.Rigf-1 LR3 dissolved at 4 ° C can be stored for 2-7 days and used up as soon as possible.To not use for short periods, store at - 20 ℃.Use as soon as possible after opening to avoid contamination.Limitations of useIt is suitable for research, laboratory and production use only and cannot be used directly in humans. Specifications and Purity: ≥90% SDS-PAGE. Molecular Weight: 7.6kD. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/R283957-SCI_6dc229ecd77f7c8065de4f696ab1d88d.pdf.
- UPC:
- 12352209
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- R283957-1mg
- CAS:
- 946870-92-4
- Product Size:
- 1mg
