Rabbit anti Human IRF7 Antibody, Recombinant, could be used for WB, IHC and so on.Application:WB: 1/500-1/1000IHC: 1/50-1/100Protein FunctionTranscriptional activator. Binds to the interferon-stimulated response element (ISRE) in IFN promoters and in the Q promoter (Qp) of EBV nuclear antigen 1 (EBNA1). Functions as a molecular switch for antiviral activity. Activated by phosphorylation in response to infection. Activation leads to nuclear retention, DNA binding, and derepression of transactivation ability.Post-translationalIn response to a viral infection, phosphorylated on the C-terminal serine cluster. Phosphorylation, and subsequent activation is inhibited by vaccinia virus protein E3. TRAF6-mediated ubiquitination is required for IRF7 activation. Specification: ExactAb™, Validated, Recombinant, 1.29 mg/mL
- UPC:
- 41106500
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Ab111230-1ml
- Product Size:
- 1ml
