Rabbit anti Human PDCD4 Antibody, Recombinant, could be used for WB and so on.Application:WB: 1/500 - 1/1000Protein FunctionInhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA.Post-translationalPolyubiquitinated, leading to its proteasomal degradation. Rapidly degraded in response to mitogens. Phosphorylation of the phosphodegron promotes interaction with BTRC and proteasomal degradation. Specification: ExactAb™, Validated, Recombinant, 0.25 mg/mL
- UPC:
- 12352203
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Ab120803-100μl
- Product Size:
- 100μl
