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Recombinant RING1 Antibody (C09-1507-168)

Aladdin

Catalog No.
C09-1507-168
Manufacturer No.
Ab125377-50μl
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $284.85
List Price: $316.50

Rabbit anti Human RING1 Antibody, Recombinant (R03-4V1), could be used for WB and so on.Application:WB: 1/500-1/1000 :Protein Function:Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A,

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Rabbit anti Human RING1 Antibody, Recombinant (R03-4V1), could be used for WB and so on.Application:WB: 1/500-1/1000 :Protein Function:Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in × chromosome inactivation of female mammals. Essential component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex act via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity. Specification: ExactAb™, Validated, Recombinant, 0.4 mg/mL
UPC:
12352203
Condition:
New
Availability:
2 weeks
Weight:
1.09 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
Ab125377-50μl
Product Size:
50μl


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