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recombinant stat3 antibody (c09-1611-311)

Recombinant STAT3 Antibody (C09-1611-311)

Aladdin

Catalog No.
C09-1611-311
Manufacturer No.
Ab129421-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $2,769.12
List Price: $3,076.79

Rabbit anti Human STAT3 Antibody, Recombinant, could be used for WB, IHC, IF/ICC and so on.Application:WB: 1/1000-1/2000IHC: 1/50-1/200IF/ICC: 1/50-1/200Protein Function:Signal transducer and transcription activator that mediates cellular responses

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Rabbit anti Human STAT3 Antibody, Recombinant, could be used for WB, IHC, IF/ICC and so on.Application:WB: 1/1000-1/2000IHC: 1/50-1/200IF/ICC: 1/50-1/200Protein Function:Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene (PubMed:17344214). May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, such as CCND1 (PubMed:17344214). Mediates the effects of LEP on melanocortin production, body energy homeostasis and lactation (By similarity). May play an apoptotic role by transctivating BIRC5 expression under LEP activation (PubMed:18242580). Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Specification: ExactAb™, Validated, KD, Recombinant, Lot by Lot
UPC:
41116126
Condition:
New
Availability:
4-8 weeks
Weight:
1.09 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
Ab129421-1ml
Product Size:
1ml


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