Rabbit anti Human Ube2N / Ubc13 Antibody, Recombinant (R07-8X9), could be used for WB and so on.Application:· WB: 1/500-1/1000:Protein Function:The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly-ubiquitination of PCNA upon genotoxic stress, which is required for DNA repair. Appears to act together with E3 ligase RNF5 in the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD. Specifications and Purity: ExactAb™, Validated, Carrier Free, Recombinant, 0.7 mg/mL
- UPC:
- 41116126
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Ab133260-10μl
- Product Size:
- 10μl
