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redox responsive poly(ethylene glycol)-block-poly(lactide-alt-glycolide) peg average mnã¡5 000 plga mnã¡15 000 (c15-1313-252)

REDOX RESPONSIVE POLY(ETHYLENE GLYCOL)-BLOCK-POLY(LACTIDE-ALT-GLYCOLIDE) PEG AVERAGE MNá5 000 PLGA MNá15 000 (C15-1313-252)

Sigma Aldrich

Catalog No.
C15-1313-252
Manufacturer No.
926248-1G
Manufacturer Name
Sigma-Aldrich
Quantity
1
Unit of Measure
GR
Price: $1,227.44
List Price: $1,363.83

Application PEG- SS -PLGA is a redox responsive, biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(lactide-alternative-glycolide) (PLGA) block , with a reducible disulfide linkage between blocks.

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Application

PEG-SS-PLGA is a redox responsive, biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(lactide-alternative-glycolide) (PLGA) block, with a reducible disulfide linkage between blocks. This polymer can be fabricated into Glutathione (GSH) responsive nanoparticles which can be used as an intracellular drug delivery system.

Different from common Poly(lactide-co-glycolide) (PLGA) polymer, the lactic and glycolic units in Poly(lactide-alt-glycolide) block alternate in sequence in the polymer chain, and the molar ratio of lactic to glycolic units in the polymer is exactly 1:1.

Poly(lactide-alt-glycolide) exhibits excellent solubility in common organic solvents, such as acetonitrile, acetone, dioxane, DCM, and THF, providing great convenience for drug delivery researches and applications.

linearFormula: CH3O(C2H4O)nC7H12O4S2(C5H6O4)m. form: powder, chunks or granules. Quality Level: 100. mol wt: PEG average Mn 5000, PLGA Mn 15000. storage temp.: 2-8°C. SMILES string: O: C(C(C)OC(CO[H]): O)OCCSSCCOC(OCCOCCOC): O. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
UPC:
51111906
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
926248-1G

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