RIPASUDIL HYDROCHLORIDE (C005B-309737)

Catalog No.: C005B-309737
Mfr. No.: SML3000-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $283.96

List Price: $315.51

Biochem/physiol Actions Ripasudil (K-115) is a more potent and selective rho-associated protein kinase (ROCK) inhibitor (IC50 = 51 nM/ROCK1, 19 nM/ROCK2, 2.1 μ:M/PKACα:, 27 μ:M/PKC, and 0.

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Description
Specifications

Biochem/physiol Actions

Ripasudil (K-115) is a more potent and selective rho-associated protein kinase (ROCK) inhibitor (IC50 = 51 nM/ROCK1, 19 nM/ROCK2, 2.1 μM/PKACα, 27 μM/PKC, and 0.37 μM/CaMKII?) than Y-27632 and HA-1077 (Fasudil). Ripasudil demonstrates in vivo efficacy in reducing intraocular pressure (IOP) by stimulating aqueous humour drainage through the trabecular meshwork.

UPC:: 51434403
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML3000-5MG
CAS:: 223645-67-8

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