Application
Ritonavir has been used:
- as a human immunodeficiency virus (HIV) protease inhibitor to study its effects on placental endocrine function
- as an HIV protease inhibitor to study its effects on reduction of tetrazolium dye in human embryonic kidney cells
- as an organic anion transporting polypeptide (OATP) inhibitor to study its effect on hepatic uptake of bergapten and imperatorin
Biochem/physiol Actions
Ritonavir is an HIV protease inhibitor now used frequently as a booster of other protease inhbitors. Ritonavir inhibits cytochrome P450-3A4 (CYP3A4), a liver enzyme that normally metabolizes protease inhibitors. It has also been investigated as a possible anti-cancer agent.
Features and Benefits
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- UPC:
- 12352200
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SML0491-10MG
- CAS:
- 155213-67-5
