RNA Polymerase III Inhibitor is a cell-permeable indazolo-sulfonamide compound that displays broad-spectrum inhibitory activity against RNA Polymerase III. RNA Polymerase III Inhibitor inhibits cell growth in yeast by preventing RNA Pol III-mediated tRNA transcription. RNA Polymerase III Inhibitor is able to compromise the structural integrity of viroplasms and rotavirus double-layered particles. When combined with an HDAC inhibtor, RNA Polymerase III Inhibitor was shown induce cell cycle arrest and apoptotic cell death in pancreatic adenocarcinoma cells.
Specification: ≥97%
Molecular Formula: C19H15Cl2N3O2S2
Molecular Weight: 452.37
PubChem CID: 2824289
Isomeric SMILES: CC1=C(SC2=C1C=C(C=C2)Cl)C3=NN(C(=C3)NS(=O)(=O)C4=CC=CC=C4Cl)C
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/R341689-SCI_8a41331253d560ac767b553ed4cfdcba.pdf
- UPC:
- 51171910
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 0.07 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- R341689-25mg
- CAS:
- 577784-91-9
- Product Size:
- 25mg
- Precautionary Statement Codes:
- P264