Rp-8-Br-cGMPS is a cell permeable cGMP analog which blocks cGMP-dependent protein kinase. This compound has been shown to suppress sodium nitroprusside-induced luteinizing hormone-releasing hormone (LHRH) secretion from GT1-7 cells. Experiments using isolated rabbit aorta contracted by phenylephrine have shown that Rp-8-Br-cGMPS competitively inhibits relaxation elicited by 8-BR-cGMP. Additionally Rp-8-Br-cGMPS has displayed the capacity to reverse exogenous NO enhanced random migration of peritoneal neutrophils in rabbit models. Specification: 0.98 Molecular Formula: C10H10BrN5NaO6PS Molecular Weight: 462.15 PubChem CID: 77519100 Isomeric SMILES: C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=NC(=NC(=O)C4N=C3Br)N)O)OP(=S)(O1)[O-].[Na+] Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/R339994-SCI_74ec0763d3ddd7fc0d20380fab09d646.pdf
- UPC:
- 12352208
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- R339994-500μg
- CAS:
- 208445-06-1
- Product Size:
- 500μg
- Precautionary Statement Codes:
- P264
