General description
Naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum. Has many complex effects on Ca2+ transport and action in muscle.
Naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum. Has many complex effects on Ca2+ transport and action in muscle. Purified from Ryanodine Mixture.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Ca2+ transport and action in muscle
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Harmful (C)
Reconstitution
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.
Other Notes
Sorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci.14, 98.
Sabbadini, R., et al. 1992. J. Biol. Chem.267, 15475.
Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta813, 77.
Marban, E., and Wier, W.G. 1985. Circ. Res.56, 133.
Sukto, J.L., et al. 1985. Fed. Proc.44, 2984.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51162508
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 559276-500UG
- CAS:
- 15662-33-6
