RYR1-SELECTIVE INHIBITOR 1 (C005B-309206)

Catalog No.: C005B-309206
Mfr. No.: SML3308-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $237.03

List Price: $263.36

Biochem/physiol Actions RyR1-selective inhibitor 1 (6,7-(methylenedioxy)-1-octyl-4-quinolone-3-carboxylic acid) potently and selectively inhibits the type 1 ryanodine receptor (RyR1). It prevents and treats malignant hyperthermia and heat stroke

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Description
Specifications

Biochem/physiol Actions

RyR1-selective inhibitor 1 (6,7-(methylenedioxy)-1-octyl-4-quinolone-3-carboxylic acid) potently and selectively inhibits the type 1 ryanodine receptor (RyR1). It prevents and treats malignant hyperthermia and heat stroke in several mouse models. RyR1-selective inhibitor 1 decreases resting intracellular Ca2+, inhibits halothane- and isoflurane-induced Ca2+ release, and suppresses caffeine-induced contracture in skeletal muscle.

UPC:: 51144601
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML3308-5MG

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