(S)-(−)-2-Methyl-CBS-oxazaborolidine solution (C09-1045-157)

ApplicationExcellent catalyst for asymmetric reductions. CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis ( S )-(-)-2-Methyl-CBS-oxazaborolidine solution [1M in toluene] may be used as a catalyst in the multi-step synthesis of (-)-diospongin A. It may also be used in the preparation of: (1 S )-2-azido-1-(2,2-dimethyl-4 H -1,3-benzodioxin-6-yl)ethanol ( R )-α-deuteriobenzyl alcohol ( R )-2-(1-hydroxyethyl)benzo[ b ]thiophene Catalyst employed in an enantioselective synthesis of ( S )-2-amino-1-phenylethanol. The CBS (Corey-Bakshi-Shibata) oxazaborolidine catalyst has been used in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C 2 -symmetrical ferrocenyl diols, and propargyl alcohols.Other NotesPrecipitate may form in storage, but does not affect product quality. Gently heat product to 80-90 °C under an inert atmosphere to redissolve solids. Specification: 1 M in toluene Molecular Formula: C18H20BNO Molecular Weight: 277.17 PubChem CID: 2734713 Isomeric SMILES: B1(N2CCC[C@H]2C(O1)(C3=CC=CC=C3)C4=CC=CC=C4)C Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/S431489-SCI_2e12e96053c75eb3c603840e4e9c8d1d.pdf