Sauchinone is a diastereomeric ligand with cytoprotective and antioxidant activities in cultured hepatocytes. Sauchinone is an inhibitor of LPS-inducible iNOS (NOS II), TNF-α and Cox-2 expression in macrophages through suppression of IκBα phosphorylation and p65 nuclear translocation and of C/EBP and/or AP-1 activation, which may have constitutive anti-inflammatory effects. Sauchinone also acts as a suppressor of NF-κB by inhibiting transactivation activity of the RelA subunit and inhibits staurosporine-induced apoptosis. Sauchinone inhibits RANKL-induced osteoclastogenesis by reducing ROS generation. Specification: 0.98 Molecular Formula: C20H20O6 Molecular Weight: 356.37 PubChem CID: 11725801 Isomeric SMILES: C[C@@H]1C[C@@H]2[C@H]3[C@@H]([C@H]1C)C4=CC5=C(C=C4O[C@@]36C(=CC2=O)OCO6)OCO5 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/S335795-SCI_e8abd0dbffa6f52f31fba33321ef8f6a.pdf
- UPC:
- 12352115
- Condition:
- New
- Availability:
- 1 day
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S335795-5mg
- CAS:
- 177931-17-8
- Product Size:
- 5mg
- Precautionary Statement Codes:
- P264
